The PCAN-ISA card (as well as the PCAN-PC/104 card) must be run in a PC with APIC mode disabled. If you need to change this low-level setting in the BIOS setup, usually Windows cannot restart afterwards - a reinstallation or a repair installation of the OS is necessary.
Fortunately, this can be circumvented by installing the necessary driver in Windows before switching off the APIC mode in the BIOS setup.

The corresponding procedure is posted in the following thread:
viewtopic.php?t=252
Mark